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Rose bengal sodium - Provectus Biopharmaceuticals

Drug Profile

Rose bengal sodium - Provectus Biopharmaceuticals

Alternative Names: PH-10; Provecta; PV-10; Rose bengal; Rose bengal disodium; Rose bengal sodium I 125; Rose bengal sodium I 131; Xantryl

Latest Information Update: 21 Nov 2018

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At a glance

  • Originator Photogen Technologies Inc.
  • Developer Pediatric Oncology Experimental Therapeutics Investigators Consortium; Provectus Biopharmaceuticals
  • Class Antiacnes; Antineoplastics; Antipsoriatics; Antivirals; Fluoresceins; Skin disorder therapies; Small molecules
  • Mechanism of Action Cell death stimulants; Cell membrane modulators; Dendritic cell stimulants; Immunostimulants; Interferon modulators; Interleukin 17 modulators; Interleukin-22 modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Liver cancer; Neuroblastoma; Malignant melanoma
  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Malignant melanoma
  • Phase II Atopic dermatitis; Psoriasis
  • Phase I Liver cancer; Liver metastases; Neuroendocrine tumours
  • Preclinical Cancer
  • Discontinued Acne vulgaris; Breast cancer

Most Recent Events

  • 14 Nov 2018 Provectus completes two toxicology studies using carbon-14- (14C-) labeled rose bengal disodium
  • 14 Nov 2018 Provectus plans a clinical trial for Atopic dermatitis in 2019
  • 05 Nov 2018 Rose bengal sodium receives Orphan Drug status for Neuroblastoma in USA
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