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Drug Profile


Alternative Names: Anivamersen; Pegnivacogin; Pegnivacogin/anivamersen; RB 006; RB 006/RB 007; RB 007; REG-1; REG-2; Revolixys

Latest Information Update: 14 Nov 2016

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At a glance

  • Originator Archemix Corporation
  • Developer Tobira Therapeutics
  • Class Anticoagulants; Antidotes; Antithrombotics; Nucleotide aptamers; Oligonucleotides
  • Mechanism of Action Factor IXa inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute coronary syndromes; Venous thrombosis

Most Recent Events

  • 01 Nov 2016 Tobira Therapeutics has been acquired by Allergan
  • 05 May 2015 Regado Biosciences has merged with Tobira Therapeutics and renamed Tobira Therapeutics
  • 25 Aug 2014 Regado Biosciences permanently terminates enrolment in the phase III REGULATE-PCI trial (NCT01848106)
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