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Research programme: 2-Methoxyestradiol analogues - EntreMed

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Drug Profile

Research programme: 2-Methoxyestradiol analogues - EntreMed

Alternative Names: 5171; 883; 900

Latest Information Update: 19 Dec 2008

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At a glance

  • Originator EntreMed
  • Class Estradiol congeners; Estrenes
  • Mechanism of Action Angiogenesis inhibitors; Apoptosis stimulants; Hypoxia-inducible factor 1 alpha inhibitors; Mitosis inhibitors; Tubulin inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No

Highest Development Phases

  • Discontinued Cancer

Most Recent Events

  • 19 Dec 2008 Discontinued - Preclinical for Cancer in USA (PO)
  • 05 Dec 2005 Data presented at the 17th AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics (AACR-NCI-EORTC-2005) have been added to the adverse events and pharmacokinetics sections
  • 14 Oct 2005 Preclinical data from a media release have been added to the Cancer pharmacodynamics section

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