Intepirdine - Axovant Sciences/GlaxoSmithKline

Drug Profile

Intepirdine - Axovant Sciences/GlaxoSmithKline

Alternative Names: 742457; GSK 742457; RVT-101; SB-742457

Latest Information Update: 27 Mar 2018

Price : $50 *
* Final gross price and currency may vary according to local VAT and billing address.
* Your purchase entitles you to full access to the information contained in our drug profile at the time of purchase. A link to download a PDF version of the drug profile will be included in your email receipt. Adis is an information provider. We do not sell or distribute the pharmaceutical compounds written about in this database.

At a glance

  • Originator GlaxoSmithKline
  • Developer Axovant Sciences; GlaxoSmithKline
  • Class Antidementias; Nootropics
  • Mechanism of Action Serotonin 6 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Alzheimer's disease; Dementia; Lewy body disease

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 01 Mar 2018 Axovant Sciences terminates the phase III MINDSET EXTENSION trial for Alzheimer's disease (Treatment-experienced) in USA, Argentina, Australia, Bulgaria, Canada, Chile, Croatia, Czech Republic, France, Germany, Italy, South Korea, Poland, Serbia, Singapore, Slovakia, Spain, Taiwan, and the United Kingdom (PO) (NCT02586909)
  • 13 Feb 2018 Axovant Sciences terminates the phase II/III HEADWAY-DLB Extension trial as intepirdine did not meet its primary efficacy endpoints in the lead-in study RVT-101-2001 for Lewy body disease in USA, United Kingdom, Spain, Netherlands, Canada, France and Italy (PO, Tablet) (NCT02928445)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top