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Interleukin 7 - Revimmune SAS

Drug Profile

Interleukin 7 - Revimmune SAS

Alternative Names: CYT 107; Glycosylated recombinant human interleukin-7 - Cytheris; IL-7; Recombinant human interleukin-7 - Cytheris; rhIL-7; Second-generation CYT 99 007

Latest Information Update: 20 Mar 2024

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At a glance

  • Originator Cytheris
  • Developer Cognate BioServices; Cytheris; National Cancer Institute (USA); National Institute of Allergy and Infectious Diseases; Revimmune SAS; Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins; The French National Agency for Research on AIDS and Viral Hepatitis; University Hospital Limoges; Washington University School of Medicine
  • Class Antineoplastics; Antiretrovirals; Cytokines; Interleukins; Recombinant proteins
  • Mechanism of Action Interleukin 7 replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Bladder cancer; Breast cancer; Colorectal cancer; HIV infections; Lymphopenia; Nontuberculous mycobacterium infections; Prostate cancer; Sepsis; Urogenital cancer
  • Suspended Idiopathic CD4-positive T-lymphocytopenia
  • Discontinued Bone marrow transplant rejection; Hepatitis B; Hepatitis C; Progressive multifocal leukoencephalopathy

Most Recent Events

  • 25 Jan 2024 Updated efficacy and adverse events data from a phase II trial in Urogenital cancer presented at the 2024 Genitourinary Cancers Symposium (ASCO-GeCS-2024)
  • 20 Oct 2023 Safety and efficacy data from the phase II trial in Urogenital cancer presented at the 48th European Society for Medical Oncology Congress (ESMO-2023)
  • 08 Apr 2022 Revimmune in collaboration with Washington University School of Medicine terminates a phase II (ILIAD-7-US-I) trial in Lymphopenia (COVID-19 infection) in USA (IM), due to poor accrual (NCT04442178)
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