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Paclitaxel liposomal - Syncore Biotechnology

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Drug Profile

Paclitaxel liposomal - Syncore Biotechnology

Alternative Names: EndoTAG-1; MBT-0206; SB 05

Latest Information Update: 04 Jan 2024

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At a glance

  • Originator University of California at San Francisco
  • Developer Jules Bordet Institute; MediGene AG; SynCore Biotechnology
  • Class Antineoplastics; Diterpenes; Paclitaxels; Skin disorder therapies; Small molecules; Taxanes; Vascular disorder therapies
  • Mechanism of Action Angiogenesis inhibitors; Mitosis inhibitors; Platelet-derived growth factor inhibitors; Proto-oncogene protein c-bcl-2 inhibitors; Tubulin inhibitors; Tubulin polymerisation promoters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pancreatic cancer
  • New Molecular Entity No
  • Available For Licensing Yes - Pancreatic cancer

Highest Development Phases

  • Phase III Triple negative breast cancer
  • Phase II Pancreatic cancer
  • No development reported Colorectal cancer; Gastrointestinal cancer; HER2 negative breast cancer; Liver cancer; Prostate cancer

Most Recent Events

  • 04 Jan 2024 No development reported - Phase-III for Pancreatic cancer (Combination therapy, Inoperable/Unresectable, Late-stage disease, Metastatic disease, Second-line therapy or greater) in Taiwan, USA, Russia, South Korea, Israel, Hungary, France (IV) (Syncore Biotechnology Pipeline January 2024)
  • 08 Dec 2022 SynCore Biotechnology terminates Phase-III trial in Triple negative Breast cancer (Metastatic disease, First-line therapy, Combination therapy) in Taiwan (IV) due to study design reconsideration (NCT03002103)
  • 19 Feb 2021 Phase III development in Pancreatic cancer (Combination therapy, Second-line therapy or greater) is still ongoing in France, Hungary and Taiwan (IV) (SynCore Biotechnology's pipeline, February 2021)
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