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Elagolix - Abbvie/Neurocrine Biosciences

Drug Profile

Elagolix - Abbvie/Neurocrine Biosciences

Alternative Names: ABT-620; Elagolix sodium; NBI-56418; ORIAHNN; ORILISSA

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator Icahn School of Medicine at Mount Sinai
  • Developer AbbVie; Neurocrine Biosciences
  • Class Analgesics; Antineoplastics; Fluorinated hydrocarbons; Pyrimidines; Small molecules
  • Mechanism of Action LHRH receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Endometriosis; Menorrhagia; Pain
  • Phase III Uterine leiomyoma
  • Phase II Polycystic ovary syndrome
  • Discontinued Benign prostatic hyperplasia; Prostate cancer

Most Recent Events

  • 27 Apr 2021 AbbVie completes a phase III trial for Menorrhagia associated with uterine fibroids in the USA and Puerto Rico (PO) (NCT03886220)
  • 10 Feb 2021 AbbVie completes a phase II trial for Polycystic ovary syndrome in Puerto Rico and USA (PO) (NCT03951077)
  • 16 Nov 2020 AbbVie plans the observational ENDORSE clinical trial for moderate to severe endometriosis-associated Pain in Israel (PO, Tablet) , (NCT04630990)
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