Research programme: complement factor 5a inhibitors - Jerini

Drug Profile

Research programme: complement factor 5a inhibitors - Jerini

Alternative Names: JPE-1375; JSM-1375; JSM-7717

Latest Information Update: 24 Mar 2010

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At a glance

  • Originator Jerini
  • Developer Jerini; Jerini Ophthalmic
  • Class Small molecules
  • Mechanism of Action Complement C5a inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Age-related macular degeneration; Inflammation

Most Recent Events

  • 10 Apr 2008 Jerini Ophthalmic signs an exclusive licensing and development agreement with PR Pharmaceuticals to develop sustained-release formulations for a variety of ophthalmic indications, including JPE 1375 for age-related macular degeneration
  • 09 Nov 2007 JSM 7717 and JPE 1375 are available for partnering for renal therapy (
  • 09 Nov 2007 JPE 1375 is available for licensing (
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