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Dapirolizumab pegol - Biogen/UCB

Drug Profile

Dapirolizumab pegol - Biogen/UCB

Alternative Names: Anti-CD40L Fab; Anti-CD40L Fab-PEG; CD40L - Fab; CDP-7657; Peg-dapirolizumab; Pegylated anti-CD40L antibody

Latest Information Update: 15 Feb 2019

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At a glance

  • Originator Biogen Idec; UCB
  • Developer Biogen; UCB
  • Class Antibodies; Fab fragments; Monoclonal antibodies; Polyethylene glycols
  • Mechanism of Action CD40 ligand inhibitors; Immunomodulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Systemic lupus erythematosus
  • No development reported Amyotrophic lateral sclerosis; Rheumatoid arthritis

Most Recent Events

  • 15 Nov 2018 UCB completes a phase II trial in Systemic lupus erythematosus (Adjunctive treatment) in USA, Bulgaria, Germany, Hungary, Spain, Ukraine, Russia, Romania, Poland, Peru, Mexico, Colombia, Chile (IV) (NCT02804763)
  • 23 Oct 2018 Top-line efficacy and adverse events data from a phase IIb trial in Systemic lupus erythematosus released by UCB and Biogen
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Systemic-lupus-erythematosus in Belgium (Parenteral)
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