Drug Profile

Vorsetuzumab mafodotin

Alternative Names: SGN-75

Latest Information Update: 18 Dec 2023

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At a glance

Originator Seattle Genetics
Class Antineoplastics; Auristatins; Drug conjugates; Immunotoxins; Monoclonal antibodies
Mechanism of Action Tubulin polymerisation inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

Highest Development Phases

Discontinued Non-Hodgkin's lymphoma; Renal cancer

Most Recent Events

14 Dec 2023 Seagen has been acquired by Pfizer
08 Oct 2020 Seattle Genetics is now called Seagen
31 Dec 2013 Seattle Genetics terminates phase I trial in Renal cancer (combination therapy) in USA (NCT01677390)

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