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Research programme: microRNA therapeutics - Regulus Therapeutics

Drug Profile

Research programme: microRNA therapeutics - Regulus Therapeutics

Alternative Names: anti-miR-10b; anti-miR-122; miR-296; miR-34; miR-34a; miR-K12-11 (viral oncomir); miR-X; miRNA therapeutics - Regulus Therapeutics; RGLS 5579; Viral microRNAs - Regulus Therapeutics

Latest Information Update: 11 Jan 2019

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At a glance

  • Originator California Institute of Technology/CalTech; Stanford University
  • Developer Cenix BioScience; Regulus Therapeutics
  • Class Antihyperglycaemics; Antisense oligonucleotides; Antivirals; Cardiovascular therapies; Hepatoprotectants; MicroRNAs
  • Mechanism of Action MicroRNA inhibitors; MicroRNA modulators; RNA interference
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Glioblastoma; Hepatitis B; Hepatitis C; Non-alcoholic steatohepatitis
  • Discontinued Diabetes mellitus; Heart failure; Metabolic syndrome; Viral infections

Most Recent Events

  • 08 Jan 2019 Pharmacodynamics data from preclinical studies in Glioblastoma released by Regulus Therapeutics
  • 20 Nov 2018 Updated pharmacodynamic data from preclinical study in Glioblastoma released by Regulus Therapeutics
  • 26 Sep 2018 Pharmacodynamics data from preclinical studies in Non-alcoholic steatohepatitis, Glioblastoma and Hepatitis B released by Regulus Therapeutics
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