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Hydronidone - Shanghai Genomics

Drug Profile

Hydronidone - Shanghai Genomics

Alternative Names: F-351

Latest Information Update: 09 Oct 2018

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At a glance

  • Originator Shanghai Genomics
  • Class Antifibrotics; Nonsteroidal anti-inflammatories; Small molecules
  • Mechanism of Action Collagen inhibitors; Fibroblast growth factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Hepatic fibrosis
  • Preclinical Renal failure
  • Discontinued Pulmonary fibrosis

Most Recent Events

  • 28 Sep 2018 Independent data monitoring committee recommends early completion of enrolment based on positive efficacy data in a phase II trial for Hepatic fibrosis in China
  • 28 Sep 2018 Shanghai Genomics plans a phase III trial for Hepatic fibrosis in China
  • 24 Apr 2018 Phase-I clinical trials in Hepatic fibrosis in USA (PO)
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