Research programme: NeuGene antisense compounds - Sarepta Therapeutics

Drug Profile

Research programme: NeuGene antisense compounds - Sarepta Therapeutics

Alternative Names: AVI 4179; AVI 4451; AVI 4XXX; NeuBiotics

Latest Information Update: 18 Apr 2013

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At a glance

  • Originator AVI BioPharma
  • Developer Sarepta Therapeutics
  • Class Antisense oligonucleotides; Morpholines
  • Mechanism of Action Genetic transcription inhibitors; HMG-CoA reductase inhibitors; Intercellular adhesion molecule 1 antagonists; Intercellular adhesion molecule 3 antagonists; NF-kappa B inhibitors; Nitric oxide synthase inhibitors; Proto-oncogene protein c-myc modulators; RNA interference; RNA synthesis inhibitors; Testosterone congener inhibitors; Transforming growth factor beta stimulants; Tumour necrosis factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Anthrax; Bacterial infections; Ricin poisoning
  • Discontinued Coronary artery restenosis; Hypercholesterolaemia; Immunological disorders; Inflammation; Multiple sclerosis; Prostate cancer; Stem cell mobilisation

Most Recent Events

  • 18 Apr 2013 No development reported - Preclinical for Anthrax in USA (Parenteral)
  • 18 Apr 2013 No development reported - Preclinical for Bacterial infections in USA (Parenteral)
  • 12 Jul 2012 AVI BioPharma is now called Sarepta Therapeutics
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