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MEDI 8968

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Drug Profile

MEDI 8968

Alternative Names: AMG-108; Anti-IL-1R MAb; MEDI-8968

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Amgen
  • Developer Amgen; MedImmune
  • Class Anti-inflammatories; Antihyperglycaemics; Antirheumatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Interleukin 1 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Chronic obstructive pulmonary disease; Hidradenitis suppurativa; Osteoarthritis; Rheumatoid arthritis; Type 2 diabetes mellitus

Most Recent Events

  • 21 Jul 2016 AstraZeneca terminates a phase II trial in Hidradenitis suppurativa in USA (SC) (NCT01838499)
  • 31 Jul 2014 Discontinued - Phase-II for Chronic obstructive pulmonary disease in USA, United Kingdom, Bulgaria, Hungary, Czech Republic, Latvia, Lithuania, Poland, Ukraine and the Philippines (SC)
  • 31 Jul 2014 Discontinued - Phase-II for Hidradenitis suppurativa in USA (SC)

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