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Research programme: cytotoxic conjugates of disorazoles - COSCIENS Biopharma

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Drug Profile

Research programme: cytotoxic conjugates of disorazoles - COSCIENS Biopharma

Alternative Names: AEZS-125; AEZS-137; AEZS-138; Disorazol; Disorazol A; Disorazol A1; Disorazol E; Disorazol E1; Disorazol Z; Disorazol Z-D-Lys6-LHRH conjugate; LHRH-disorazol Z

Latest Information Update: 08 Aug 2024

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At a glance

  • Originator GBF
  • Developer COSCIENS Biopharma; Helmholtz Centre for Infection Research GmbH
  • Class Drug conjugates; Macrolides; Oxazoles
  • Mechanism of Action Apoptosis stimulants; LHRH receptor modulators; Mitosis inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • No development reported Solid tumours

Most Recent Events

  • 06 Aug 2024 AEterna Zentaris Inc is now called COSCIENS Biopharma
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Solid-tumours in Germany (Parenteral)
  • 13 Jan 2016 AEterna Zentaris has patent protection for disorazol Z and the LHRH receptor antagonist in 15 countries

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