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Amonafide malate

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Drug Profile

Amonafide malate

Alternative Names: Amonafide L-malate; Amonafide maleate; AS 1413; Xanafide

Latest Information Update: 02 Oct 2021

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At a glance

  • Originator Xanthus Pharmaceuticals
  • Developer Antisoma; Xanthus Pharmaceuticals
  • Class Amines; Antineoplastics; Isoquinolines; Naphthalimides; Small molecules
  • Mechanism of Action DNA intercalators; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia
  • Available For Licensing Yes - Acute myeloid leukaemia

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Breast cancer; Prostate cancer

Most Recent Events

  • 31 Jan 2011 Discontinued - Phase-III for Acute myeloid leukaemia in Australia (IV)
  • 31 Jan 2011 Discontinued - Phase-III for Acute myeloid leukaemia in Canada (IV)
  • 31 Jan 2011 Discontinued - Phase-III for Acute myeloid leukaemia in Eastern Europe (IV)

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