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PD 325901

Drug Profile

PD 325901

Alternative Names: PD-0325901; PD-325901

Latest Information Update: 09 Nov 2018

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At a glance

  • Originator Pfizer
  • Developer AstraZeneca; BIOENSIS; Pfizer; SpringWorks Therapeutics; University of Alabama at Birmingham; University of Oxford
  • Class Aniline compounds; Anti-inflammatories; Antineoplastics; Benzamides; Immunotherapies; Small molecules
  • Mechanism of Action MAP kinase kinase 1 inhibitors; MAP kinase kinase 2 inhibitors; Mitogen-activated protein kinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Neurofibromatoses
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Neurofibromatoses
  • Preclinical Cervical cancer; Chronic obstructive pulmonary disease
  • No development reported Colorectal cancer
  • Discontinued Breast cancer; Cancer; Malignant melanoma; Non-small cell lung cancer

Most Recent Events

  • 05 Nov 2018 PD 325901 receives Orphan Drug status for Neurofibromatosis in USA
  • 05 Sep 2018 PD 325901 is available for licensing as of 05 Sep 2018. http://www.springworkstx.com/
  • 05 Sep 2018 SpringWorks Therapeutics and BeiGene enters into global clinical collaboration for Solid Tumors
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