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Research programme: tyrosine kinase inhibitors - SuperGen

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Drug Profile

Research programme: tyrosine kinase inhibitors - SuperGen

Alternative Names: MP-371

Latest Information Update: 27 Apr 2010

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At a glance

  • Originator SuperGen
  • Class Small molecules
  • Mechanism of Action Aurora kinase A inhibitors; CSK protein inhibitors; Platelet-derived growth factor alpha receptor antagonists; Platelet-derived growth factor beta receptor antagonists; Protein tyrosine kinase inhibitors; Proto-oncogene protein c-kit inhibitors; Proto-oncogene protein c-met inhibitors; Proto-oncogene protein c-ret inhibitors; Rad51 recombinase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Cancer

Most Recent Events

  • 11 May 2007 Data presented at the 98th Annual Meeting of the American Association for Cancer Research (AACR-2007) added to the adverse events and pharmacokinetics a sections
  • 25 Apr 2007 SuperGen receives approval from the FDA to initiate phase I trials of MP 470 in solid tumours
  • 05 Apr 2006 Montigen has been acquired and merged into SuperGen

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