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Research programme: fusion protein therapeutics - Altor BioScience

Drug Profile

Research programme: fusion protein therapeutics - Altor BioScience

Alternative Names: 264scTCR/IgG1; ALT-802; ALT-804; Antiviral TCR - Ab; Antiviral TCR - Ck; IMPACT™ fusion proteins research programme - Altor BioScience; N-820; STAR-based therapeutics research programme - Altor BioScience; STAR-IMPACT; T cell receptor IgG1 fusion protein; T cell receptor IL-2 fusion protein

Latest Information Update: 03 Jan 2019

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At a glance

  • Originator Altor BioScience Corporation; Massachusetts General Hospital
  • Class Recombinant fusion proteins
  • Mechanism of Action Immunomodulators; Interleukin 15 receptor antagonists; Interleukin-15 receptor agonists; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Preclinical Burkitt's lymphoma
  • No development reported Autoimmune disorders; Cancer; Multiple sclerosis; Rheumatoid arthritis; Type 1 diabetes mellitus; Viral infections

Most Recent Events

  • 01 Dec 2018 Preclinical trials in Burkitt's lymphoma in USA (unspecified route)
  • 01 Dec 2018 Pharmacodynamics data from a preclinical trial in Burkitt's lymphoma presented at the 60th Annual Meeting and Exposition of the American Society of Hematology (ASH-2018)
  • 04 Nov 2017 No recent reports of development identified for preclinical development in Autoimmune-disorders in USA
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