Research programme: fusion protein therapeutics - Altor BioScience
Alternative Names: 264scTCR/IgG1; ALT-802; ALT-804; Antiviral TCR - Ab; Antiviral TCR - Ck; IMPACT™ fusion proteins research programme - Altor BioScience; N-820; STAR-based therapeutics research programme - Altor BioScience; STAR-IMPACT; T cell receptor IgG1 fusion protein; T cell receptor IL-2 fusion proteinLatest Information Update: 28 Jan 2023
At a glance
- Originator Altor BioScience Corporation; Massachusetts General Hospital
- Class Recombinant fusion proteins
- Mechanism of Action Immunomodulators; Interleukin 15 receptor agonists; Interleukin 15 receptor antagonists; T lymphocyte stimulants
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
- Available For Licensing Yes
Highest Development Phases
- No development reported Autoimmune disorders; Burkitt's lymphoma; Cancer; Multiple sclerosis; Rheumatoid arthritis; Type 1 diabetes mellitus; Viral infections
Most Recent Events
- 28 Jan 2023 No recent reports of development identified for preclinical development in Burkitt's-lymphoma in USA
- 01 Dec 2018 Preclinical trials in Burkitt's lymphoma in USA (unspecified route)
- 01 Dec 2018 Pharmacodynamics data from a preclinical trial in Burkitt's lymphoma presented at the 60th Annual Meeting and Exposition of the American Society of Hematology (ASH-2018)