Research programme: opioid receptor like-1 antagonists - Brane Discovery

Drug Profile

Research programme: opioid receptor like-1 antagonists - Brane Discovery

Alternative Names: 819555; 848814; BND-001; BND-1 programme; GSK 819555; GSK 848814; NiK-001; ORL-1 orphan receptor antagonists; ORL-1 programme; SB 612111

Latest Information Update: 11 Feb 2009

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At a glance

  • Originator GlaxoSmithKline
  • Developer Brane Discovery
  • Class Small molecules
  • Mechanism of Action Adenylate cyclase stimulants; Calcium channel agonists; G protein-coupled receptor antagonists; Opioid receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued CNS disorders; Neuropathic pain; Parkinson's disease

Most Recent Events

  • 12 Jun 2007 This programme is available for partnership opportunities (
  • 04 Jun 2007 Brane Discovery acquires this research programme from NiKem Research
  • 04 Jun 2007 Preclinical trials in Parkinson's disease in Italy (PO)
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