CMP 001

Drug Profile

CMP 001

Alternative Names: ARB 1598; CMP-001; CYT 003 QbetaG10; CYT-003; CYT003 PolQb; CYT003 PolQbeta; CYT003-QbG10; Immunodrug™ CYT003-QbG10; QbG10; Virus-like particle-based cancer vaccine - Checkmate; VLP-based cancer vaccine - Checkmate

Latest Information Update: 14 Sep 2018

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At a glance

  • Originator Cytos Biotechnology
  • Developer Arbutus Biopharma; Checkmate Pharmaceuticals; Cytos Biotechnology; University of Pittsburgh
  • Class Allergy immunotherapies; Antiallergics; Cancer vaccines; Oligonucleotides; Virus-like particle vaccines
  • Mechanism of Action Toll-like receptor 9 agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Phase II Malignant melanoma
  • Phase I Non-small cell lung cancer
  • Preclinical Lymphoma
  • Discontinued Allergic asthma; Atopic dermatitis; Hepatitis B; Perennial allergic rhinitis; Seasonal allergic rhinitis

Most Recent Events

  • 05 Sep 2018 Checkmate Pharmaceuticals enters into a strategic collaboration with Merck KGaA, and Pfizer for Head and neck cancer
  • 05 Sep 2018 Checkmate Pharmaceuticals in collaboration with Merck KGaA and Pfizer plans a phase Ib/II trial for Head and neck cancer (Combination therapy)
  • 15 Aug 2018 Checkmate Pharmaceuticals plans a phase II trial for Malignant Melanoma (Late-stage disease, Combination therapy) in August 2018 (NCT03618641)
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