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Plinabulin - BeyondSpring Pharmaceuticals

Drug Profile

Plinabulin - BeyondSpring Pharmaceuticals

Alternative Names: BPI 2358; NPI 2358

Latest Information Update: 23 Oct 2019

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At a glance

  • Originator Nereus Pharmaceuticals
  • Developer BeyondSpring Pharmaceuticals; Big Ten Cancer Research Consortium; National Cancer Institute (USA); Nereus Pharmaceuticals; Rutgers Cancer Institute of New Jersey; University of Washington
  • Class Antineoplastics; Imidazoles; Piperazines; Small molecules
  • Mechanism of Action Guanine nucleotide exchange factor stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Neutropenia; Non-small cell lung cancer
  • Phase I/II Small cell lung cancer
  • No development reported Brain cancer; Glioblastoma; Solid tumours

Most Recent Events

  • 23 Oct 2019 BeyondSpring announces intention to submit a NDA to China’s National Medical Products Administration (NMPA) for chemotherapy-induced Neutropenia and Non-small cell lung cancer in first quarter of 2020
  • 23 Oct 2019 BeyondSpring announces intention to submit the NDA to US FDA for chemotherapy induced Neutropenia and Non-small cell lung cancer in year 2020
  • 17 Oct 2019 BeyondSprings Pharmaceuticals has patent protection for plinabulin for the treatment of Glioblastoma multiforme and other brain tumours in USA
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