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Burixafor - GPCR Therapeutics

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Drug Profile

Burixafor - GPCR Therapeutics

Alternative Names: GP 01; GPC-100; TG-0054; TG-3000

Latest Information Update: 12 Dec 2025

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At a glance

  • Originator TaiGen Biotechnology
  • Developer GPCR Therapeutics; TaiGen Biotechnology
  • Class Amines; Anti-ischaemics; Cyclohexanes; Eye disorder therapies; Methylamines; Piperazines; Propylamines; Pyrimidines; Small molecules
  • Mechanism of Action CXCR4 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Stem cell mobilisation
  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Stem cell mobilisation
  • No development reported Age-related macular degeneration; Diabetic retinopathy

Most Recent Events

  • 08 Dec 2025 Efficacy and safety data from a phase II trial in Stem cell mobilization released by Exicure
  • 08 Dec 2025 Pharmacodynamics data from a preclinical trial in Stem cell mobilization released by Exicure
  • 03 Nov 2025 GPCR Therapeutics and Exicure completes a phase II trial in Stem cell mobilization (Combination therapy) in USA (IV, Infusion) (NCT05561751)

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