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BNC 105

Drug Profile

BNC 105

Alternative Names: BNC 105P; BNC-105

Latest Information Update: 28 May 2018

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At a glance

  • Originator Iliad Chemicals
  • Developer Bionomics
  • Class Anisoles; Antineoplastics; Benzofurans; Small molecules
  • Mechanism of Action Angiogenesis inhibitors; Apoptosis stimulants; Tubulin polymerisation inhibitors; Vascular disrupting agents
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes

Highest Development Phases

  • Phase II Mesothelioma; Renal cell carcinoma
  • Phase I/II Ovarian cancer
  • Preclinical Colorectal cancer
  • No development reported Chronic lymphocytic leukaemia

Most Recent Events

  • 24 Jun 2018 Biomarkers information updated
  • 28 May 2018 No recent reports of development identified for preclinical development in Chronic-lymphocytic-leukaemia in Australia
  • 05 Mar 2018 Dartmouth-Hitchcock Medical Center plans a phase I trial of BNC 105P (Combination therapy, Second-line therapy or greater) in Chronic lymphocytic leukaemia in March 2018 (NCT03454165)
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