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MM 111

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Drug Profile

MM 111

Alternative Names: MM-111

Latest Information Update: 08 Apr 2020

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At a glance

  • Originator Merrimack Pharmaceuticals
  • Class Antineoplastics; Bispecific antibodies; Recombinant fusion proteins
  • Mechanism of Action ERBB 2 receptor antagonists; ERBB-3 receptor antagonists; Neuregulin-1 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Gastric cancer; Oesophageal cancer
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Gastric cancer; HER2 positive breast cancer; Oesophageal cancer; Solid tumours

Most Recent Events

  • 30 May 2019 Merrimack Pharmaceuticals enters into an agreement with Elevation Oncology to divest MM 111 for Cancer
  • 26 Feb 2015 9175306 - Merrimack stops enrolment in phase II trial
  • 26 Feb 2015 Discontinued - Phase-I for HER2-positive-breast cancer (Combination therapy, Late-stage disease, Recurrent, Second-line therapy or greater) in USA (IV)

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