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Anamorelin - Helsinn Therapeutics/Ono Pharmaceutical

Drug Profile

Anamorelin - Helsinn Therapeutics/Ono Pharmaceutical

Alternative Names: Adlumiz; Anamorelin HCl; Anamorelin hydrochloride; ONO-7643; RC-1291; RC-1291 HCl; ST-1291

Latest Information Update: 11 Apr 2020

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At a glance

  • Originator Novo Nordisk
  • Developer Helsinn Therapeutics; Ono Pharmaceutical
  • Class Appetite stimulants; Piperidines; Small molecules
  • Mechanism of Action Ghrelin receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Anorexia; Cachexia
  • Phase II Fatigue

Most Recent Events

  • 25 Feb 2020 Curtin University initiates the phase II ANTHEM trial in Cachexia (associated with malignant mesothelioma) in Australia (PO) (ACTRN12619001324101)
  • 15 Aug 2019 Ono Pharmaceutical completes a phase III trial in Cachexia in Japan (PO) (JapicCTI-163426)
  • 16 Jul 2019 Tufts University and National Institute of Arthritis and Musculoskeletal and Skin Diseases plans a phase I trial for Metabolic bone diseases and Muscular atrophy in the US in August 2019 (NCT04021706)
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