2-iminobiotin - Neurophyxia
Alternative Names: 2-IB; 2-Iminobiotin; NeufixLatest Information Update: 02 Oct 2021
Price :
$50 *
At a glance
- Originator Neurophyxia
- Developer Neurophyxia; University Medical Center Utrecht
- Class Imidazoles; Neuroprotectants; Pentanoic acids; Small molecules
- Mechanism of Action Nitric oxide synthase type I inhibitors; Nitric oxide synthase type II inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II Asphyxia
Most Recent Events
- 03 Feb 2020 Phase II development is still ongoing for 2-iminobiotin for Asphyxia (Neurophyxia pipeline, February 2020)
- 28 Sep 2017 University Medical Centre Utrecht and Neurophyxia completes a phase II trial in Asphyxia (In infants) in Netherlands (IV), before September 2017 (EudraCT2014-004265-25)
- 23 May 2017 Neurophyxia terminates a phase II trial in Asphyxia (In neonates) because recruitment too slow and site decided to use hypothermia (exclusion criteria) in Turkey and Lithuania (IV) (NCT01626924)