Pegcantratinib - Sienna Biopharmaceuticals
Alternative Names: CT 301/P; CT 327; K-252a-PEG2K; Pegylated K252A; SNA-120Latest Information Update: 01 Apr 2021
At a glance
- Originator Cephalon
- Developer Sienna Biopharmaceuticals
- Class Antipsoriatics; Carbazoles; Indole alkaloids; Skin disorder therapies; Small molecules
- Mechanism of Action TrkA receptor antagonists
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Atopic dermatitis; Neuropathic pain; Plaque psoriasis; Pruritus
Most Recent Events
- 14 May 2019 Sienna Biopharmaceuticals completes End-of-Phase II meeting with the US FDA
- 14 May 2019 Updated efficacy results from a phase IIb trial in Psoriasis released by Sienna Biopharmaceuticals
- 14 Mar 2019 Sienna Biopharmaceuticals schedules an End-of-Phase 2 (EOP2) meeting with the US FDA in April 2019