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Pegcantratinib - Sienna Biopharmaceuticals

Drug Profile

Pegcantratinib - Sienna Biopharmaceuticals

Alternative Names: CT 301/P; CT 327; K-252a-PEG2K; Pegylated K252A; SNA-120

Latest Information Update: 04 Jul 2019

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At a glance

  • Originator Cephalon
  • Developer Creabilis SA; Sienna Biopharmaceuticals
  • Class Antipsoriatics; Carbazoles; Indole alkaloids; Skin disorder therapies; Small molecules
  • Mechanism of Action TrkA receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Atopic dermatitis; Plaque psoriasis; Pruritus
  • Discontinued Neuropathic pain

Most Recent Events

  • 14 May 2019 Sienna Biopharmaceuticals completes End-of-Phase II meeting with the US FDA
  • 14 May 2019 Updated efficacy results from a phase IIb trial in Psoriasis released by Sienna Biopharmaceuticals
  • 14 Mar 2019 Sienna Biopharmaceuticals schedules an End-of-Phase 2 (EOP2) meeting with the US FDA in April 2019
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