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Avacincaptad pegol - IVERIC bio

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Drug Profile

Avacincaptad pegol - IVERIC bio

Alternative Names: ACP; Anti-C5 aptamer; ARC-1905; ASP-3021; Avacincaptad pegol sodium; IZERVAY; Zimura

Latest Information Update: 28 May 2026

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At a glance

  • Originator Archemix Corporation
  • Developer IVERIC bio
  • Class Eye disorder therapies; Oligonucleotides; Polyethylene glycols
  • Mechanism of Action Complement C5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Dry age-related macular degeneration
  • Phase II Polypoidal choroidal vasculopathy; Wet age-related macular degeneration
  • Discontinued Stargardt disease

Most Recent Events

  • 15 May 2026 Preregistration for Dry age-related macular degeneration in China (Intravitreous)
  • 15 May 2026 Avacincaptad pegol granted Priority Review status in China
  • 15 May 2026 The National Medical Products Administration (NMPA) accepts NDA for avacincaptad pegol for the treatment of geographic atrophy secondary to age-related macular degeneration

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