Avacincaptad pegol - Ophthotech Corporation

Drug Profile

Avacincaptad pegol - Ophthotech Corporation

Alternative Names: Anti-C5 aptamer; ARC-187; ARC-1905; Avacincaptad pegol sodium; Zimura

Latest Information Update: 06 Aug 2018

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At a glance

  • Originator Archemix Corporation
  • Developer OphthoTech Corporation
  • Class Eye disorder therapies; Oligonucleotides; Polyethylene glycols
  • Mechanism of Action Complement C5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Dry age-related macular degeneration
  • Phase II Polypoidal choroidal vasculopathy; Stargardt disease; Wet age-related macular degeneration

Most Recent Events

  • 01 Aug 2018 Ophthotech Corporation completes enrolment in a phase IIa trial for Wet age-related macular degeneration in USA and Hungary
  • 16 Jan 2018 Ophthotech initiates enrolment in a phase IIb trial for Stargardt disease 1 in USA (NCT03364153; 9231320)
  • 11 Dec 2017 Phase-II clinical trials in Wet age-related macular degeneration (Combination therapy) in Hungary (Intravitreous) (EudraCT2017-003923-31)
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