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Avacincaptad pegol - Ophthotech Corporation

Drug Profile

Avacincaptad pegol - Ophthotech Corporation

Alternative Names: Anti-C5 aptamer; ARC-187; ARC-1905; Avacincaptad pegol sodium; Zimura

Latest Information Update: 28 Nov 2018

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At a glance

  • Originator Archemix Corporation
  • Developer OphthoTech Corporation
  • Class Eye disorder therapies; Oligonucleotides; Polyethylene glycols
  • Mechanism of Action Complement C5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Dry age-related macular degeneration; Polypoidal choroidal vasculopathy; Stargardt disease; Wet age-related macular degeneration

Most Recent Events

  • 12 Nov 2018 Efficacy and adverse events data from a phase IIa trial in Wet -age related macular degeneration released by Ophthotech Corporation
  • 18 Oct 2018 Ophthotech Corporation completes a phase II trial inWet age-related macular degeneration (Combination therapy, Treatment-naive) in Latvia, Hungary and USA (NCT03362190) (EudraCT2017-003923-31)
  • 04 Oct 2018 Ophthotech Corporation completes enrolment in a phase IIb trial for Dry age related macular degeneration in USA, Croatia, Czech Republic, Estonia, Hungary, Israel and Latvia
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