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Egaptivon pegol

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Drug Profile

Egaptivon pegol

Alternative Names: ARC1779

Latest Information Update: 12 Aug 2015

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At a glance

  • Originator Archemix Corporation
  • Class Antithrombotics; Nucleotide aptamers; Polyethylene glycols
  • Mechanism of Action Von Willebrand factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Thrombotic thrombocytopenic purpura
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Haemolytic uraemic syndrome; Thrombosis; Thrombotic thrombocytopenic purpura; Von Willebrand disease

Most Recent Events

  • 12 Feb 2010 A phase IIa trial in cerebral embolism discontinued because of slow enrolment
  • 31 Mar 2009 Archemix initiates enrolment in a phase IIa trial for thrombosis prevention (in patients undergoing carotid endarterectomy) in Europe and North America
  • 28 Jan 2009 Phase-II clinical trials in Haemolytic uraemic syndrome in Europe (IV)
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