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Recombinant human histone H1.3

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Drug Profile

Recombinant human histone H1.3

Alternative Names: OncoHist; Product F - SymbioTec; rhH1.3; SYN-20051504RU; SYN-20051604RU

Latest Information Update: 16 Apr 2021

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At a glance

  • Originator SymbioTec
  • Developer Dana-Farber Cancer Institute; Pharmsynthez; SymbioTec; Xenetic Biosciences
  • Class Antineoplastics; Biological proteins; Recombinant proteins
  • Mechanism of Action Apoptosis stimulants; Cell membrane modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Acute myeloid leukaemia; Precursor cell lymphoblastic leukaemia-lymphoma
  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Acute myeloid leukaemia; Non-Hodgkin's lymphoma

Most Recent Events

  • 16 Apr 2021 Discontinued - Phase-I/II for Acute myeloid leukaemia in Germany (IV)
  • 16 Apr 2021 Discontinued - Phase-II for Acute myeloid leukaemia (Combination therapy, Second-line therapy or greater) in Russia (IV)
  • 16 Apr 2021 Discontinued - Phase-II for Non-Hodgkin's lymphoma (Second-line therapy or greater) in Russia (IV)

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