Selexipag - Actelion/Nippon Shinyaku

Drug Profile

Selexipag - Actelion/Nippon Shinyaku

Alternative Names: ACT-293987; NS-304; Uptravi

Latest Information Update: 12 Jun 2018

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At a glance

  • Originator Nippon Shinyaku
  • Developer Actelion Pharmaceuticals; Nippon Shinyaku
  • Class Acetamides; Antihypertensives; Pyrazines; Small molecules; Sulfonamides; Vasodilators
  • Mechanism of Action Epoprostenol receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary arterial hypertension
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Pulmonary arterial hypertension
  • Phase III Arteriosclerosis obliterans; Pulmonary hypertension
  • Phase II Raynaud's disease; Spinal stenosis

Most Recent Events

  • 29 May 2018 Actelion completes a phase III trial for Pulmonary arterial hypertension in Germany and USA (NCT03187678)
  • 18 May 2018 Actelion completes a phase I trial in Healthy volunteers in Belgium (NCT03496506)
  • 09 May 2018 Phase-II clinical trials in Spinal stenosis (unspecified route) (Nippon Shinyaku pipeline, May 2018)
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