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Anifrolumab - Bristol-Myers Squibb/MedImmune

Drug Profile

Anifrolumab - Bristol-Myers Squibb/MedImmune

Alternative Names: Anti-IFNaR MAb - Medarex/MedImmune; MDX-1333; MEDI-546

Latest Information Update: 22 Jan 2019

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At a glance

  • Originator Medarex
  • Developer Medarex; Medical University of Vienna; MedImmune
  • Class Antirheumatics; Monoclonal antibodies; Skin disorder therapies
  • Mechanism of Action Interferon alpha beta receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III Systemic lupus erythematosus
  • Phase II Lupus nephritis; Rheumatoid arthritis
  • Discontinued Scleroderma

Most Recent Events

  • 28 Dec 2018 No recent reports of development identified for phase-I development in Systemic-lupus-erythematosus(In volunteers) in USA (SC, Infusion)
  • 17 Dec 2018 AstraZeneca completes a phase II trial in Systemic lupus erythematosus in USA, Poland, Hungary and South Korea (NCT02962960)
  • 27 Sep 2018 AstraZeneca completes the phase III TULIP 2 trial in Systemic lupus erythematosus in USA, Spain, Lithuania, Argentina, Belgium, Brazil, Bulgaria, Canada, Czech Republic, France, Germany, Japan, South Korea, Mexico, Russia, Singapore and South Africa (IV) (NCT02446899) (EudraCT2014-004632-19)
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