Upamostat - Link Health Group/RedHill Biopharma
Alternative Names: Mesupron; RHB-107; WX-671Latest Information Update: 03 Sep 2024
At a glance
- Originator Wilex
- Developer Heidelberg Pharma AG; Link Health Group; RedHill Biopharma; WILEX AG
- Class Amines; Antineoplastics; Antivirals; Imides; Piperazines; Small molecules; Sulfonamides
- Mechanism of Action Serine endopeptidase inhibitors; Urokinase-type plasminogen activator inhibitors; Virus internalisation inhibitors; Virus replication inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase II/III COVID 2019 infections
- Phase II Breast cancer; Pancreatic cancer
- Clinical Phase Unknown Gastrointestinal disorders
- Preclinical Ebola virus infections; Influenza virus infections
- No development reported Cancer; Cholangiocarcinoma; Solid tumours
- Discontinued Head and neck cancer
Most Recent Events
- 29 Aug 2024 Pharmacodynamics data from a preclinical studies in Ebola virus infections released by RedHill Biopharma
- 28 Jul 2024 No recent reports of development identified for preclinical development in Cholangiocarcinoma in Israel (PO)
- 28 Apr 2024 No recent reports of development identified for preclinical development in COVID-2019-infections in Israel (PO)