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Mannitol inhalation - Pharmaxis

Drug Profile

Mannitol inhalation - Pharmaxis

Alternative Names: Bronchitol; Mannitol dry powder for inhalation - Pharmaxis; Precision spray‐dried mannitol

Latest Information Update: 12 Feb 2019

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At a glance

  • Originator Royal Prince Alfred Hospital
  • Developer Pharmaxis
  • Class Antibronchitics; Antifibrotics; Diagnostic agents; Small molecules; Sugar alcohols
  • Mechanism of Action Osmotic diuretics
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cystic fibrosis; Bronchiectasis
  • New Molecular Entity No
  • Available For Licensing Yes - Bronchiectasis; Cystic fibrosis

Highest Development Phases

  • Marketed Cystic fibrosis
  • Discontinued Allergic rhinitis; Bronchiectasis; Sinusitis

Most Recent Events

  • 12 Feb 2019 Discontinued - Phase-III for Bronchiectasis in New Zealand, United Kingdom, Australia, USA, Germany, Argentina, Belgium, Chile, Netherlands (Inhalation)
  • 12 Feb 2019 Launched for Cystic fibrosis (Adjunctive treatment) in Cyprus (Inhalation), prior to February 2019
  • 12 Feb 2019 Launched for Cystic fibrosis (Adjunctive treatment) in Estonia (Inhalation), prior to February 2019
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