Drug Profile

Manganese chloride tetrahydrate - Ascelia Pharma

Alternative Names: CMC-001; Mangoral^®; Orviglance

Latest Information Update: 19 Nov 2025

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At a glance

Originator CMC Contrast
Developer Ascelia Pharma
Class Contrast media; Heavy metals
Mechanism of Action Magnetic resonance imaging enhancers

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

Yes - Liver disorders
New Molecular Entity No

Highest Development Phases

Preregistration Liver disorders

Most Recent Events

10 Nov 2025 Ascelia Pharma files for patent protection with the patent authority for manganese chloride tetrahydrate (Orviglance^®)
03 Sep 2025 Preregistration for Liver disorders (Diagnosis) in USA (PO)
08 Apr 2025 Ascelia Pharma plans NDA submission to US FDA for Liver disorders (Diagnosis) in mid-2025

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