Research programme: antibody-drug conjugates - ImClone/Seagen

Alternative Names: Antibody-drug conjugates research programme - ImClone/Seagen; EB10-MMAF

Latest Information Update: 18 Dec 2023

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At a glance

Originator ImClone Systems; Seattle Genetics
Class Auristatins; Immunotoxins; Monoclonal antibodies
Mechanism of Action Apoptosis stimulants; Mitosis inhibitors; Tubulin inhibitors; Tubulin polymerisation inhibitors

Orphan Drug Status

Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

No
New Molecular Entity Yes

14 Dec 2023 Seagen has been acquired by Pfizer
08 Oct 2020 Seattle Genetics is now called Seagen
20 Oct 2004 Preclinical trials in Acute myeloid leukaemia in USA (unspecified route)

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