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Chlormethine - Actelion Pharmaceuticals/Helsinn

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Drug Profile

Chlormethine - Actelion Pharmaceuticals/Helsinn

Alternative Names: Clearazide™; Ledaga; LEDAGATM; Mechlorethamine gel; Nitrogen mustard topical gel; Topical nitrogen mustard; Valchlor

Latest Information Update: 31 Dec 2024

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At a glance

  • Originator Yaupon Therapeutics
  • Developer Actelion Pharmaceuticals; Helsinn; Orphan Europe; Recordati Rare Diseases
  • Class Antineoplastics; Nitrogen mustard compounds; Small molecules
  • Mechanism of Action Alkylating agents; T-cell receptor gene inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Mycosis fungoides; Cutaneous T-cell lymphoma
  • New Molecular Entity No

Highest Development Phases

  • Marketed Mycosis fungoides

Most Recent Events

  • 02 Dec 2024 No development reported - Preregistration for Mycosis fungoides in China (Topical)
  • 18 Oct 2022 Pharmacodynamics data from a preclinical in vitro study in Mycosis fungoides released by Helsinn
  • 21 Sep 2022 Launched for Mycosis fungoides (Second-line therapy or greater, In adults) in Canada (Topical) before September 2022

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