Scyllo-inositol - Transition Therapeutics Ireland

Drug Profile

Scyllo-inositol - Transition Therapeutics Ireland

Alternative Names: AZD-103; ELND-005; Quercinitol; Scyllitol; Scyllocyclohexanehexol; Scylloinositol

Latest Information Update: 30 Jan 2018

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At a glance

  • Originator Transition Therapeutics
  • Developer Speranza Therapeutics; Transition Therapeutics Ireland
  • Class Antidementias; Cyclohexanols; Nootropics; Small molecules
  • Mechanism of Action Amyloid beta-protein inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II/III Alzheimer's disease
  • Phase II Down syndrome
  • Discontinued Bipolar disorders

Most Recent Events

  • 30 Jan 2018 Scyllo-inositol is still at phase II/III for Alzheimer's disease (for the treatment of agitation and aggression) in Canada, Spain, USA and United Kingdom and at phase II for Down syndrome in USA (PO) (Transition Therapeutics pipeline, January 2018)
  • 31 Aug 2016 Transition Therapeutics has been acquired by OPKO Health
  • 15 Oct 2015 Efficacy and safety data from the phase II/III HARMONY AD trial released by Transition Therapeutics
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