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Tiprelestat - Proteo Biotech

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Drug Profile

Tiprelestat - Proteo Biotech

Alternative Names: Elafin

Latest Information Update: 23 Jul 2018

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At a glance

  • Originator Proteo Biotech
  • Developer Proteo Biotech; Rhein Minapharm Biogenetics; Stanford University
  • Class Anti-inflammatories; Antihypertensives; Antipsoriatics; Recombinant proteins
  • Mechanism of Action Leucocyte elastase inhibitors; Myeloblastin inhibitors; Pancreatic elastase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pulmonary arterial hypertension; Pulmonary hypertension; Oesophageal cancer; Postoperative inflammation
  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Myocardial reperfusion injury; Postoperative inflammation
  • Preclinical Lung disorders; Lung transplant rejection; Pulmonary arterial hypertension

Most Recent Events

  • 17 Jul 2018 Pharmacodynamics data from a preclinical study released by Proteo Biotech
  • 24 Jan 2018 Tiprelestat is still in preclinical trials for lung disorders in USA
  • 23 Jan 2018 Tiprelestat is still in phase II trials for postoperative inflammation associated with oesophagectomy for oesophageal carcinoma in Germany
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