Voruciclib - Lite Strategy
Alternative Names: ME-522; P 1446A 05; P-1446; P1446A; VoruciclibLatest Information Update: 16 Sep 2025
At a glance
- Originator Piramal Life Sciences
- Developer Lite Strategy; Piramal Enterprises
- Class Antineoplastics; Benzopyrans; Pyrones; Pyrrolidines; Small molecules
- Mechanism of Action CDC2 protein kinase inhibitors; Cyclin-dependent kinase 4 inhibitors; Cyclin-dependent kinase 6 inhibitors; Cyclin-dependent kinase 9 inhibitors
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Phase I Acute myeloid leukaemia; B-cell lymphoma
- No development reported Malignant melanoma
Most Recent Events
- 10 Sep 2025 MEI Pharma is now called Lite Strategy
- 07 Dec 2024 Updated phrmacodynamics data from the phase I trial in Acute myeloid leukemia, B-cell lymphoma presented at the 66th American Society of Hematology Annual Meeting and Exposition 2024 (ASH-Hem-2024)
- 07 Dec 2024 Updated efficacy and pharmacokinetics data from the phase I trial in Acute myeloid leukemia, B-cell lymphoma presented at the 66th American Society of Hematology Annual Meeting and Exposition 2024 (ASH-Hem-2024)