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Cariprazine - Gedeon Richter

Drug Profile

Cariprazine - Gedeon Richter

Alternative Names: Cariprazine prolonged release; MP-214; REAGILA; Reagila; RGH-188; RGH-188 HCl; SYMVENU; VRAYLAR; Vraylar; WID-RGC20

Latest Information Update: 05 Nov 2023

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At a glance

  • Originator Gedeon Richter
  • Developer AbbVie; Gedeon Richter; Mitsubishi Tanabe Pharma Corporation; Recordati; Whanin Pharmaceutical
  • Class Antidepressants; Antipsychotics; Behavioural disorder therapies; Chlorobenzenes; Cyclohexanes; Mood stabilisers; Piperazines; Small molecules; Urea compounds
  • Mechanism of Action Dopamine D2 receptor partial agonists; Dopamine D3 receptor partial agonists; Histamine H1 receptor antagonists; Serotonin 1A receptor partial agonists; Serotonin 2A receptor antagonists; Serotonin 2B receptor antagonists; Serotonin 2C receptor modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Bipolar depression; Bipolar disorders; Major depressive disorder; Schizophrenia
  • Phase III Pervasive child development disorders
  • No development reported Schizoaffective disorder

Most Recent Events

  • 07 Jun 2023 AbbVie announces Reimbursement under the Non-Insured Health Benefits (NIHB) Program for cariprazine (VRAYLAR®) for the treatment of Schizophrenia in Canada
  • 17 Apr 2023 AbbVie announces Provincial Reimbursement for cariprazine (VRAYLAR®) for the Treatment of Schizophrenia in Québec
  • 17 Dec 2022 Launched for Major depressive disorder (Adjunctive treatment, Treatment-experienced) in USA (PO)
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