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Cariprazine - Gedeon Richter

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Drug Profile

Cariprazine - Gedeon Richter

Alternative Names: Cariprazine prolonged release; MP-214; REAGILA; Reagila; RGH-188; RGH-188 HCl; SYMVENU; VRAYLAR; Vraylar; WID-RGC20

Latest Information Update: 11 Mar 2025

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At a glance

  • Originator Gedeon Richter
  • Developer AbbVie; Gedeon Richter; Mitsubishi Tanabe Pharma Corporation; Recordati; Whanin Pharmaceutical
  • Class Antidepressants; Antipsychotics; Behavioural disorder therapies; Chlorobenzenes; Cyclohexanes; Mood stabilisers; Piperazines; Small molecules; Urea compounds
  • Mechanism of Action 5-HT2C serotonin receptor modulators; Dopamine D2 receptor partial agonists; Dopamine D3 receptor partial agonists; Histamine H1 receptor antagonists; Serotonin 1A receptor partial agonists; Serotonin 2B receptor antagonists; Serotonin 5-HT2A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Bipolar depression; Bipolar disorders; Major depressive disorder; Schizophrenia
  • Phase III Autism spectrum disorder
  • No development reported Schizoaffective disorder

Most Recent Events

  • 31 Jan 2025 Registered for Major depressive disorder (Adjunctive treatment) in Thailand (unspecified route)
  • 04 Oct 2024 AbbVie completes a phase-III trial in Autism spectrum disorder (In children, In adolescents) in Puerto Rico and USA (PO) (NCT05439616)
  • 24 Sep 2024 AbbVie terminates a phase III trial in Schizophrenia in Japan and Taiwan (PO) due to business decision (NCT05368558)

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