Cariprazine - Gedeon Richter
Alternative Names: Cariprazine prolonged release; MP-214; REAGILA; Reagila; RGH-188; RGH-188 HCl; SYMVENU; VRAYLAR; Vraylar; WID-RGC20Latest Information Update: 06 Sep 2024
At a glance
- Originator Gedeon Richter
- Developer AbbVie; Gedeon Richter; Mitsubishi Tanabe Pharma Corporation; Recordati; Whanin Pharmaceutical
- Class Antidepressants; Antipsychotics; Behavioural disorder therapies; Chlorobenzenes; Cyclohexanes; Mood stabilisers; Piperazines; Small molecules; Urea compounds
- Mechanism of Action Dopamine D2 receptor partial agonists; Dopamine D3 receptor partial agonists; Histamine H1 receptor antagonists; Serotonin 1A receptor partial agonists; Serotonin 2A receptor antagonists; Serotonin 2B receptor antagonists; Serotonin 2C receptor modulators
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Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
- New Molecular Entity Yes
Highest Development Phases
- Marketed Bipolar depression; Bipolar disorders; Major depressive disorder; Schizophrenia
- Phase III Pervasive child development disorders
- No development reported Schizoaffective disorder
Most Recent Events
- 04 Sep 2024 AbbVie receives a positive reimbursement recommendation from Canada's Drug Agency (CDA) for Schizophrenia in adults
- 07 Jun 2023 AbbVie announces Reimbursement under the Non-Insured Health Benefits (NIHB) Program for cariprazine (VRAYLAR®) for the treatment of Schizophrenia in Canada
- 17 Apr 2023 AbbVie announces Provincial Reimbursement for cariprazine (VRAYLAR®) for the Treatment of Schizophrenia in Québec