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Moxifloxacin/dexamethasone

Drug Profile

Moxifloxacin/dexamethasone

Alternative Names: AL-15469A/AL-38905; AL-15469A/AL-38905 ophthalmic formulation - Alcon Research; MoxiDex Otic; VIGADEXA

Latest Information Update: 15 Apr 2019

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At a glance

  • Originator Alcon
  • Class Anti-inflammatories; Aza compounds; Fluorinated steroids; Pregnadienetriols; Quinolines
  • Mechanism of Action DNA gyrase inhibitors; Glucocorticoid receptor agonists; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Ocular inflammation; Ophthalmic infections
  • Discontinued Corneal disorders; Otitis externa; Otitis media

Most Recent Events

  • 09 Apr 2019 Novartis completed the spin-off of Alcon
  • 05 Apr 2018 Novartis Pharmaceuticals in collaboration with Alcon Research plans a phase II trial for Otitis Externa (In children, In adolescents, In adults, In the elderly) in the US (EudraCT2018-000641-39)
  • 24 Mar 2014 Alcon withdraws a phase III trial for Ocular inflammation and infection (prevention) in Brazil prior to enrolment (NCT01515826) (Ophthalmic, gel)
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