Nelotanserin - Axovant Sciences

Drug Profile

Nelotanserin - Axovant Sciences

Alternative Names: APD-125; RVT-102

Latest Information Update: 12 Jan 2018

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At a glance

  • Originator Arena Pharmaceuticals
  • Developer Arena Pharmaceuticals; Axovant Sciences
  • Class Antidementias; Antiparkinsonians; Sleep disorder therapies; Small molecules
  • Mechanism of Action Serotonin 2A receptor inverse agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Lewy body disease
  • Discontinued Insomnia

Most Recent Events

  • 08 Jan 2018 Efficacy data from a phase II trial in Lewy body disease released by Axovant Sciences
  • 01 Nov 2017 Axovant Sciences completes a phase II trial in Lewy body disease (In adults, In the elderly) in USA (PO) (NCT02640729)
  • 19 Jun 2017 Nelotanserin receives Fast Track designation for Lewy body disease [PO,Tablet] (In adolescents, In children) in USA
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